ALS, often referred to as Lou Gehrig's disease, causes progressive muscle paralysis and is one of the most common forms of motor neuron disease (MND). Symptoms typically begin with muscle twitching or weakness, followed by difficulty in speech. As the disease progresses, individuals may lose the ability to perform basic functions such as eating, walking, and even breathing without assistance. Unfortunately, there is currently no known cure for ALS, and the prognosis is typically limited to a few years to decades post-diagnosis, depending on the individual.

Dane's career spans various hit shows and films, including his iconic role as Dr. Mark Sloan in "Grey's Anatomy," and he is married to actress Rebecca Gayheart, with whom he shares two children. As he continues to work through this challenging time, Dane has requested privacy for himself and his family while they navigate his health journey, showcasing his resilience and commitment to his craft.